Craig C. Mello (1960- )
نویسندگان
چکیده
Craig C. Mello is an American developmental biologist and Nobel Laureate, who helped discover RNA interference [4] (RNAi). Along with his colleague Andrew Fire [5], he developed gene knockouts using RNAi. In 2006 Mello won the Nobel Prize in Physiology or Medicine [6] for his contribution to the discovery of RNAi. Mello also contributed to developmental biology, focusing on gene regulation [7], cell signaling, cleavage formation, germline determination [8], cell migration [9], cell fate differentiation [10], and morphogenesis.
منابع مشابه
A Co-CRISPR Strategy for Efficient Genome Editing in C. elegans
1 A Co-CRISPR Strategy for Efficient Genome Editing in C. elegans Heesun Kim, Takao Ishidate, Krishna S. Ghanta, Meetu Seth, Darryl Conte Jr., Masaki Shirayama, and Craig C. Mello Program in Molecular Medicine, RNA Therapeutics Institute, and †Howard Hughes Medical Institute, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA 01605, USA These authors contributed eq...
متن کامل1 A Co - CRISPR Strategy for Efficient Genome Editing in C . elegans
1 A Co-CRISPR Strategy for Efficient Genome Editing in C. elegans Heesun Kim, Takao Ishidate, Krishna S. Ghanta, Meetu Seth, Darryl Conte Jr., Masaki Shirayama, and Craig C. Mello Program in Molecular Medicine, RNA Therapeutics Institute, and †Howard Hughes Medical Institute, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA 01605, USA These authors contributed eq...
متن کاملSnail Protein Family in Drosophila Neurogenesis: a Dissertation
................................................................................ ...... CHAPTER I: INTRODUCTION.......................................................... ... OVERVIEW................................................................................... . Brief account of Drosophila embryonic development.................................. Maternal Genes in Development. . .
متن کاملThe Nobel Prize in Physiology or Medicine for 2006 jointly to Andrew Fire and Craig Mello
An adult human being has about 100 000 billion cells. The nucleus of each cell carries all our genetic material: a total of two meters of DNA containing some 30 000 genes. When genes are expressed (activated), genetic information is copied from DNA to messenger molecules, messenger RNA (mRNA), which then orchestrate formation of proteins. Proteins are involved in the life processes of all organ...
متن کاملWnt and CDK-1 regulate cortical release of WRM-1/beta-catenin to control cell division orientation in early Caenorhabditis elegans embryos
1 regulate cortical release of WRM-1/beta-catenin to control cell division orientation in early Caenorhabditis elegans embryos"
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